Search results for " social problem"
showing 10 items of 76 documents
Eduardo Sojo: The architect of the satirical journalism in Spain and Argentina
2016
El artículo analiza la extensa obra de Eduardo Sojo a través de las publicaciones satíricas que fundó en España y en Argentina durante las últimas décadas siglo XIX. A partir de la indagación de algunas de sus caricaturas políticas se reconstruye su posicionamiento político en los diferentes contextos en los que desarrolló su obra y el impacto que suscitó en la opinión pública su discurso en favor de los valores republicanos y su reiterado repudio hacia el clero, en ambos países. This article analyzes Eduardo Sojós extensive work through the satirical publications, which he founded in Spain and Argentina during the last decades of 19 th century. By looking into some of his political cartoon…
Boosting effect of IL-7 in interferon gamma release assays to diagnose Mycobacterium tuberculosis infection.
2018
BACKGROUND A quarter of the world's population is estimated to be infected with Myobacterium tuberculosis (Mtb). Infection is detected by immune response to M. tuberculosis antigens using either tuberculin skin test (TST) and interferon gamma release (IGRA's), tests which have low sensitivity in immunocompromised. IL-7 is an important cytokine for T-cell function with potential to augment cytokine release in in-vitro assays. This study aimed to determine whether the addition of IL-7 in interferon-gamma release assays (IGRAs) improves its diagnostic performance of Mtb infection. METHODS 44 cases with confirmed TB and 45 household contacts without TB were recruited and 1ml of blood was stimul…
Proceedings of the 2nd BEAT-PCD conference and 3rd PCD training school: part 1
2018
Primary ciliary dyskinesia (PCD) is a rare heterogenous condition that causes progressive suppurative lung disease, chronic rhinosinusitis, chronic otitis media, infertility and abnormal situs. ‘Better Experimental Approaches to Treat Primary Ciliary Dyskinesia’ (BEAT-PCD) is a network of scientists and clinicians coordinating research from basic science through to clinical care with the intention of developing treatments and diagnostics that lead to improved long-term outcomes for patients. BEAT-PCD activities are supported by EU funded COST Action (BM1407). The second BEAT-PCD conference, and third PCD training school were held jointly in April 2017 in Valencia, Spain. Presentations and w…
Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history.
2021
Coscolla et al.
An international registry for primary ciliary dyskinesia
2016
Primary ciliary dyskinesia (PCD) is a rare autosomal recessive disorder leading to chronic upper and lower airway disease. Fundamental data on epidemiology, clinical presentation, course and treatment strategies are lacking in PCD. We have established an international PCD registry to realise an unmet need for an international platform to systematically collect data on incidence, clinical presentation, treatment and disease course.The registry was launched in January 2014. We used internet technology to ensure easy online access using a web browser under www.pcdregistry.eu. Data from 201 patients have been collected so far. The database is comprised of a basic data form including demographic…
Usefulness of current candidate genetic markers to identify childhood cancer patients at risk for platinum-induced ototoxicity: Results of the Europe…
2020
Background Irreversible sensorineural hearing loss is a common side effect of platinum treatment with the potential to significantly impair the neurocognitive, social and educational development of childhood cancer survivors. Genetic association studies suggest a genetic predisposition for cisplatin-induced ototoxicity. Among other candidate genes, thiopurine methyltransferase (TPMT) is considered a critical gene for susceptibility to cisplatin-induced hearing loss in the FDA drug label and a pharmacogenetic guideline. The aim of this cross-sectional cohort study was to confirm the genetic associations in a large pan-European population and to evaluate the diagnostic accuracy of the genetic…
Proceedings of the 3rd BEAT-PCD Conference and 4th PCD Training School
2018
Abstract Primary ciliary dyskinesia (PCD) is a chronic suppurative airways disease that is usually recessively inherited and has marked clinical phenotypic heterogeneity. Classic symptoms include neonatal respiratory distress, chronic rhinitis since early childhood, chronic otitis media, recurrent airway infections leading to bronchiectasis, chronic sinusitis, laterality defects with and without congenital heart disease including abnormal situs in approximately 50% of the cases, and male infertility. Lung function deteriorates progressively from childhood throughout life. ‘Better Experimental Approaches to Treat Primary Ciliary Dyskinesia’ (BEAT-PCD) is a network of scientists and clinician…
Estudio del problema social en el Hospital La Fe de Valencia desde la Unidad de Trabajo Social Hospitalario: recursos
2014
Objetivos: La investigación recoge los recursos aplicados por la Unidad de Trabajo Social Hospitalario valorando si son adecuados para solucionar la problemática detectada, así como la demora y satisfacción en los pacientes del Hospital Universitario La Fe de Valencia. Los recursos más solicitados y gestionados desde la Unidad de Trabajo Social Hospitalaria son los sociales (discapacidad, dependencia, Servicio de Ayuda a Domicilio y Servicios Sociales) siguiéndoles los sanitarios (hospital y prestaciones sanitarias complementarias). El 87,6% de los recursos se consideran adecuados para resolver la problemática planteada. El 76,5% se muestra satisfecho o complacido. El 67,5% de los pacientes…
Worldwide trends in population-based survival for children, adolescents, and young adults diagnosed with leukaemia, by subtype, during 2000–14 (CONCO…
2022
BACKGROUND Leukaemias comprise a heterogenous group of haematological malignancies. In CONCORD-3, we analysed data for children (aged 0-14 years) and adults (aged 15-99 years) diagnosed with a haematological malignancy during 2000-14 in 61 countries. Here, we aimed to examine worldwide trends in survival from leukaemia, by age and morphology, in young patients (aged 0-24 years). METHODS We analysed data from 258 population-based cancer registries in 61 countries participating in CONCORD-3 that submitted data on patients diagnosed with leukaemia. We grouped patients by age as children (0-14 years), adolescents (15-19 years), and young adults (20-24 years). We categorised leukaemia subtypes a…
Psychiatric disorders in childhood cancer survivors in Denmark, Finland, and Sweden: a register-based cohort study from the SALiCCS research programm…
2022
BACKGROUND A childhood cancer diagnosis and treatment-induced somatic late effects can affect the long-term mental health of survivors. We aimed to explore whether childhood cancer survivors are at higher risk of psychiatric disorders later in life than their siblings and the general population. METHODS In this register-based cohort study (part of the Socioeconomic Consequences in Adult Life after Childhood Cancer [SALiCCS] research programme), we included 5-year survivors of childhood cancer diagnosed before 20 years of age between Jan 1, 1974 and Dec 31, 2011, in Denmark, Finland, and Sweden. In Denmark and Sweden, 94��7% of individuals were born in a Nordic country (ie, Denmark, Finland,…